Structural Investigation and Antibacterial Activity of Cu(II), Co(II), Ni(II) and Zn(II) Complexes of a Schiff Base Derived from Salicylaldehyde and Thiosemicarbazide

The metal (II) complexes, Na2[ML2] [M = Cu, Co, Ni, and Zn], of salicylaldehyde thiosemicarbazone (L) containing a trifunctional ONS-donor system have been synthesized and characterized on the basis of physicochemical data by elemental analysis, magnetic moment, molar conductance, and spectroscopic (electronic, IR and ESI-MS). The ligand functions as ONS tridentates producing octahedral complexes. All compounds showed significant antibacterial activity in different ranges against gram positive (Bacillus subtillus) and gram negative (Escherichia coli) bacteria.