SYNTHESIS AND CHARACTERIZATION OF GRAPE SEED MEDIATED TITANIUM DIOXIDE NANOPARTICLES: AN in vitro STUDY

Background: Nanotechnology used in dentistry as dental materials have unique physicochemical and biological properties that can be used to overcome the complications caused by other traditional dental treatments. Titanium dioxide nanoparticles (NPs) have been demonstrated to be an effective multifunctional material. Grape seed extract is a rich source of polymers of flavan-3-ols like catechin and epicatechin.

Aim: The aim of the study was to synthesize and characterize grape seed mediated titanium dioxide nanoparticles using UV Visible Spectroscopy.

Materials and methods: The synthesis of the titanium dioxide nanoparticle is done with green synthesis method. Morphological characters like the shape and size of the obtained green synthesized titanium dioxide nanoparticles by transmission electron microscope.

Results: The peak value of absorbance titanium dioxide nanoparticles was found to be at 370 nm. The TEM imaging revealed that the particles were spherical shaped. The results confirmed that the green synthesis of grape seed mediated titanium dioxide nanoparticles is cost efficient and eco friendly.

Conclusion: In this study, a simple, biological and low cost approach was done for the preparation of titanium dioxide nanoparticles using grape seeds. Thus, the synthesized grape seed mediated titanium dioxide nanoparticles can be subjected to various other biological activities such as antibacterial, antifungal, cytotoxic evaluation to know the efficiency of these nanoparticles.