Focusing on the Future Efforts to Thwart Memory Loss in Alzheimer’s Disease

During the past few years, Alzheimer’s disease (AD) has been shown to be a chronic infection.
Spirochetes, Lyme Borrelia and dental treponemes, are the etiologic agents; these spirochetes make
biofilms, and, in so doing, are responsible for the formation of beta amyloid and hyperphosphorylated
tau protein. The pathways for all these components of AD has been outlined. The following are
possible future efforts based on the above information. These include attempting to culture the dental
spirochetes as well as attempting to develop a serologic test for pre-AD. A trial for early AD is
proposed, as is a possible way of preventing AD with periodic courses of effective antibiotics. This
regimen would likely need to be continued for many months. A trial prior to the onset of the disease,
would hardly be ethical, because the control arm would get AD if the microbes were unopposed.