Synthesis, Characterization and Biological Activities of Schiff Bases and Their Transition Metal Complexes

Schiff bases are versatile ligands which are synthesized from the condensation of primary amines with carbonyl groups. These compounds are very important in medicinal and pharmaceutical fields because of their wide spectrum of biological activities. Most of them show biological activities such as antibacterial, antifungal as well as antitumor activity. Transition metal complexes derived from the Schiff base ligands with biological activity have been widely studied. This summarizes the synthesis, characterization and biological activities of Schiff bases and its transition metal complexes.