Mineral and Bone Disorders in Pre-dialysis Chronic Kidney Disease

Chitralli, Deepak Kumar and Churchill, Brian Mark (2020) Mineral and Bone Disorders in Pre-dialysis Chronic Kidney Disease. International Journal of Advances in Nephrology Research, 3 (1). pp. 11-20.

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Abstract

Chronic kidney disease (CKD) affects 9.1% of the world population (estimated in 2017). The estimates indicate that globally 1.2 million people died of CKD in 2017. As kidney function declines, there is a progressive deterioration in mineral homeostasis. There are changes in circulating levels of hormones as well including parathyroid hormone (PTH), vitamin D, fibroblast growth factor-23 (FGF-23), and growth hormone. Studies have also found association between MBD and fractures, cardiovascular disease (CVD) and mortality.

It is well established that abnormalities in mineral metabolism are apparent early in the course of chronic kidney disease (CK D). This study was undertaken to assess and compare the biochemical markers of bone mineral disorders in diabetics with early CKD and non-diabetics with early CKD.

Item Type: Article
Subjects: Academic Digital Library > Medical Science
Depositing User: Unnamed user with email info@academicdigitallibrary.org
Date Deposited: 04 Apr 2023 05:39
Last Modified: 12 Mar 2024 04:23
URI: http://publications.article4sub.com/id/eprint/1069

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